Rapid manufacturing techniques for the tissue engineering of human heart valves
نویسندگان
چکیده
منابع مشابه
Rapid manufacturing techniques for the tissue engineering of human heart valves.
Three-dimensional (3D) printing technologies have reached a level of quality that justifies considering rapid manufacturing for medical applications. Herein, we introduce a new approach using 3D printing to simplify and improve the fabrication of human heart valve scaffolds by tissue engineering (TE). Custom-made human heart valve scaffolds are to be fabricated on a selective laser-sintering 3D...
متن کاملTissue engineering of heart valves--human endothelial cell seeding of detergent acellularized porcine valves.
OBJECTIVE Tissue engineering of heart valves represents a new experimental concept to improve current modes of therapy in valvular heart disease. Drawbacks of glutaraldehyde fixed tissue valves or mechanical valves include the short durability or the need for life-long anticoagulation, respectively. Both have in common the inability to grow, which makes valvular heart disease especially problem...
متن کاملDesign and fabrication of three-dimensional scaffolds for tissue engineering of human heart valves.
We developed a new fabrication technique for 3-dimensional scaffolds for tissue engineering of human heart valve tissue. A human aortic homograft was scanned with an X-ray computer tomograph. The data derived from the X-ray computed tomogram were processed by a computer-aided design program to reconstruct a human heart valve 3-dimensionally. Based on this stereolithographic model, a silicone va...
متن کاملAdvances and Trends in Tissue Engineering of Heart Valves
Improvements in health care and treatment of diseases have led to an increase in life expectancy in developed countries. However, this achievement has also inadvertently increased the prevalence of chronic illnesses such as cardiovascular disease, adding to the growing burden of health care cost globally. Unfortunately, this trend is expected to escalate in the foreseeable future. Cardiovascula...
متن کاملTissue engineering of heart valves: in vitro experiences.
BACKGROUND Tissue engineering is a new approach, whereby techniques are being developed to transplant autologous cells onto biodegradable scaffolds to ultimately form new functional tissue in vitro and in vivo. Our laboratory has focused on the tissue engineering of heart valves, and we have fabricated a trileaflet heart valve scaffold from a biodegradable polymer, a polyhydroxyalkanoate. In th...
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ژورنال
عنوان ژورنال: European Journal of Cardio-Thoracic Surgery
سال: 2014
ISSN: 1010-7940,1873-734X
DOI: 10.1093/ejcts/ezt510